Welcome

Influenza virus — a seemingly simple virus with only 8 genomic RNAs and ~ 14 proteins. But, this apparent simplicity belies complex programs deployed by the virus to steal, disable, and subvert cellular processes with the ultimate goal of replicating and transmitting new particles.

In the Mehle Lab, we study the viral replication machinery and the host factors that regulate expression of viral genes and replication of the viral genome. We are especially interested in how influenza virus usurps cellular processes to support viral replication, including those classically associated with responses thought to inhibit infection.

(Want to talk about flu or career opportunities? Email Andy with your CV and a coverletter explaining your interest and background. We’d love to hear from you.)